Afrique One-ASPIRE is a five years (2016-2021) Pan African programme which leads capacity building and research on One Health in Africa through five Thematic Training Programmes that develop pathways to intervention and elimination (Rabies, Brucellosis, TB, Foodborne diseases and Surveillance-response). After two years of training, studies design and first data analysis, Afrique One-ASPIRE fellows are taking the One Health Day to showcase of their preliminary findings and provide evidence on how One Health foster collaborations and add value in global health.