NASA Earth’s Applied Sciences Program has prepared two social media communications (Facebook: https://www.facebook.com/nasaearth/posts/pfbid02W2qugDar8mf21HPprFJ4itP… and Twitter: https://twitter.com/NASAEarth/status/1588178825917222912) for One Health Day 2022. This campaign promotes NASA Data Pathfinders (https://www.earthdata.nasa.gov/learn/pathfinders/diseases-data-pathfind…) that can serve as a guide to using Earth science data to examine environmental health topics. It also highlights two public health projects that integrate Earth observation data into public health applications – examining the health effects of urban air pollution (Child Asthma and Other Health Effects of Long-Term Urban Air Pollution: https://appliedsciences.nasa.gov/our-impact/news/child-asthma-and-other…) and forecasting West Nile virus in South Dakota (Fighting Mosquito-borne Disease with Help from Satellites: https://appliedsciences.nasa.gov/our-impact/story/fighting-mosquito-bor…). These projects demonstrate that multidisciplinary collaborations with scientists and community stakeholders are fundamental to inform public health decision-making.